6/22/2023 0 Comments Insulinoma on mri sag localizer3 Imaging plays a critical and indispensable role in NETs diagnosis, prognosis and management therefore radiologists are important members of the multidisciplinary NET team. An effective diagnosis of NET requires a multimodal approach that combines evaluation of clinical symptoms, hormone levels, radiological and nuclear imaging, and histological confirmation. 4 The diagnosis of functional (F)-p-NETs is clinical with laboratory test that should confirm the hypothesis. 3 Between 60% and 90% of GEP-NETs of pancreas (p-NETs) are non-functioning tumors, so they can be diagnosed at advanced stages because of their relatively indolent nature and slow growth. The neuroendocrine tumour of the gastroenterict tract can cause vague abdominal symptoms and may be diagnosed as an irritable bowel syndrome (IBS). Non-functioning tumours generally present non-specific symptoms and frequently manifest as locally advanced or metastatic desease. 2 Functioning tumours usually reveal themselves relatively early, so it might be difficult for the radiologist to localize the lesions since they are often too small to be detected. 1 Thanks to their capability to synthesize and secrete peptides and hormones, these tumours can cause clinical syndromes, although more often may be asymptomatic and discovered as an incidental finding. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) are a heterogeneous group of tumours, arising from neuroendocrine cells present in the gastrointestinal tract and into the islets of Langerhans of the pancreas.
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